Objetivos pedagógicos

After reading this chapter, you should be able:

  • To present the different fat signal suppression techniques
  • Describe the advantages and disadvantages of STIR sequences, fat saturation, selective excitation of water
  • Specify the different families of contrast agents
    • Explain their action on relaxation time and contrast
    • List their contraindications and main indications
  • Explain magnetization transfer and how it can improve background suppression

Pontos principais

Magnetization transfer

  • Off-resonance RF pulse in relation to the peak of water
  • Saturation of protons with restricted mobility (brain, muscle, liver)
  • Drop in signal due to exchanges between free and bound protons
  • Does not affect fluids (LCR, blood, urine) containing no bound protons


  1. Elster. Questions and answers in magnetic resonance imaging. 1994:ix, 278 p..
  2. McRobbie. MRI from picture to proton. 2003:xi, 359 p..
  3. NessAiver. All you really need to know about MRI physics. 1997.
  4. Kastler. Comprendre l'IRM. 2006.
  5. de Kerviler, Leroy-Willig. Fat suppression techniques in MRI: an update. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 1998;52(2):69-75.
  6. Gandhi, Brown. MR contrast agents for liver imaging: what, when, how. Radiographics. 2006 Nov-Dec;26(6):1621-36.
  7. Lin and Brown. MR contrast agents: Physical and pharmacologic basics. J Magn Reson Imaging. 2007 May;25(5):884-99.
  8. Sadowski, Bennett. Nephrogenic Systemic Fibrosis: Risk Factors and Incidence Estimation. Radiology. 2007 Jan 31.