Modic changes on MRI
Publication date: February 14, 2014 | Updated on February 14, 2014
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Diagnosis
Modic changes on MRI
History
Modic changes on MR imaging, are signal intensity changes in vertebral body marrow adjacent to the endplates of degenerative discs.
Modic changes
MR T1 weighted
MR T2 weighted
Signification
Modic 1
Low signal
High signal
Marrow edema.
Modic 2
High signal
High signal
Fatty degeneration of subchondral marrow.
Modic 3
Low signal
Low signal
Extensive bony sclerosis
There seems to be a very strong correlation between having Modic changes, especially Modic changes type 1, and suffering from pain in the lower back.
- Modic MT, Steinberg PM, Ross JS, et al. : "Degenerative disk disease: assessment of changes in vertebral body marrow with MR imaging". I Radiology 1988;166(1 Pt 1):193-9.
- Modic MT, Masaryk TJ, Ross JS, Carter JR. : "Imaging af degererative disk disease". I Radiology 1988;168:177-86.
- Albert HB, Kjaer P, Jensen TS, Sorensen JS, Bendix T, Manniche C : "Modic changes, possible causes and relation to low back pain.". I Med Hypotheses. 2008;70(2):361-8. Epub 2007 Jul 10
- Albert HB, Manniche C. : "Modic changes following lumbar disc herniation.". I Eur Spine J. 2007 Jul;16(7):977-82. Epub 2007 Mar 3.